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1

Newer aspects of the synthesis and chemistry of nitroxide spin labels

Keana, John F. W.

Journal:

Chemical Reviews

Year:

1978

Language:

english

File:

PDF, 2.01 MB

english, 1978

2

Functionalized Perfluorophenyl Azides: New Reagents for Photoaffinity Labeling

John F.W. Keana, Sui Xiong Cai

Journal:

Journal of Fluorine Chemistry

Year:

1989

Language:

english

File:

PDF, 171 KB

english, 1989

3

Synthesis and SAR of 5-, 6-, 7- and 8-Aza Analogues of 3-Aryl-4-hydroxyquinolin-2(1H)-one as NMDA/Glycine Site Antagonists

Zhang-Lin Zhou, James M Navratil, Sui Xiong Cai, Edward R Whittemore, Stephen A Espitia, Jon E Hawkinson, Minhtam Tran, Richard M Woodward, Eckard Weber, John F.W Keana

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 289 KB

english, 2001

4

Synthesis of diamagnetic structural analogs of representative doxyl, proxyl, piperidine, and pyrroline nitroxide spin labels

Keana, John F. W., Seyedrezai, Seyed E.

Journal:

Journal of Organic Chemistry

Year:

1982

Language:

english

File:

PDF, 835 KB

english, 1982

5

Synthesis and Structure-Activity Relationships of Substituted 1,4-Dihydroquinoxaline-2,3-diones: Antagonists of N-Methyl-D-aspartate (NMDA) Receptor Glycine Sites and Non-NMDA Glutamate Receptors

Keana, John F. W., Kher, Sunil M., Cai, Sui Xiong, Dinsmore, Christian M., Glenn, Anne G., Guastella, J., Huang, Jin-Cheng, Ilyin, Victor, Lu, Yixin

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.66 MB

english, 1995

6

Synthesis and characterization of a novel cholesterol nitroxide spin label. Application to the molecular organization of human high-density lipoprotein

Keana, John F. W., Tamura, Toshinari, McMillen, Debra A., Jost, Patricia C.

Journal:

Journal of the American Chemical Society

Year:

1981

Language:

english

File:

PDF, 1.91 MB

english, 1981

7

Synthesis of Fluorogenic Substrates for Continuous Assay of Phosphatidylinositol-Specific Phospholipase C

Zaikova, Tatiana O., Rukavishnikov, Aleksey V., Birrell, G. Bruce, Griffith, O. Hayes, Keana, John F. W.

Journal:

Bioconjugate Chemistry

Year:

2001

Language:

english

File:

PDF, 99 KB

english, 2001

8

Synthesis of Racemic 6,7,8,9-Tetrahydro-3-hydroxy-1 H -1-benzazepine-2,5-diones as Antagonists of N -Methyl- d -aspartate (NMDA) and α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid (AMPA) Receptors

Guzikowski, Anthony P., Whittemore, Edward R., Woodward, Richard M., Weber, Eckard, Keana, John F. W.

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 245 KB

english, 1997

9

Synthesis of the ABC ring system of the steroid batrachotoxin

Schumaker, Robert R., Keana, John F. W.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1972

Language:

english

File:

PDF, 124 KB

english, 1972

10

ChemInform Abstract: Synthesis of a New Fluorogenic Substrate for the Continuous Assay of Mammalian Phosphoinositide-Specific Phospholipase C.

Aleksey V. Rukavishnikov, Tatiana O. Zaikova, G. Bruce Birrell, John F. W. Keana, O. Hyes Griffith

Journal:

Year:

1999

File:

PDF, 32 KB

1999

11

ChemInform Abstract: Structure—Activity Relationship for a Series of 2-Substituted 1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indoles: Potent Subtype-Selective Inhibitors of N-Methyl-D-aspartate (NMDA) Receptors.

Amir P. Tamiz, Edward R. Whittemore, Richard M. Woodward, Ravindra B. Upasani, John F. W. Keana

Journal:

Year:

1999

File:

PDF, 33 KB

1999

12

ChemInform Abstract: A Practical Synthesis of 4-(Substituted-benzyl)piperidines and (.+-.)-3-(Substituted-benzyl)pyrrolidines via a Wittig Reaction.

Zhang-Lin Zhou, John F. W. Keana

Journal:

Year:

1999

File:

PDF, 32 KB

1999

13

Nanoscale Tripodal 1,3,5,7-Tetrasubstituted Adamantanes for AFM Applications.

Quan Li, Aleksey V. Rukavishnikov, Pavel A. Petukhov, Tatiana O. Zaikova, Changshu Jin, John F. W. Keana

Journal:

Year:

2003

File:

PDF, 52 KB

2003

14

Tritiation of the nitroxide spin labeled fatty acid 14-proxylstearic acid

John F. W. Keana, Steven A. Boyd

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1981

Language:

english

File:

PDF, 117 KB

english, 1981

15

Nitroxides as potential contrast enhancing agents for MRI application: Influence of structure on the rate of reduction by rat hepatocytes, whole liver homogenate, subcellular fractions, and ascorbate

John F. W. Keana, Sovitj Pou, Gerald M. Rosen

Journal:

Magnetic Resonance in Medicine

Year:

1987

Language:

english

File:

PDF, 642 KB

english, 1987

16

Interactions of nitroxides with plasma and blood: Effect on 1/T1 of water protons

Harold F. Bennett, Rodney D. Brown, John F. W. Keana, Seymour H. Koenig, Harold M. Swartz

Journal:

Magnetic Resonance in Medicine

Year:

1990

Language:

english

File:

PDF, 893 KB

english, 1990

17

A fluorescent substrate for the continuous assay of phosphatidylinositol-specific phospholipase C: Synthesis and application of 2-naphthyl myo-inositol-1-phosphate

M.S. Shashidhar, Johannes J. Volwerk, John F.W. Keana, O. Hayes Griffith

Journal:

Analytical Biochemistry

Year:

1991

Language:

english

File:

PDF, 598 KB

english, 1991

18

Stearoyl paratoluenesulfonate. A powerful acylating agent for lipid synthesis

John F.W. Keana, Alan R. Ertle

Journal:

Chemistry and Physics of Lipids

Year:

1976

Language:

english

File:

PDF, 366 KB

english, 1976

19

Saturated and unsaturated lipid spin labels with terminally located nitroxide groups

John F.W. Keana, Lawrence E. La Fleur

Journal:

Chemistry and Physics of Lipids

Year:

1979

Language:

english

File:

PDF, 668 KB

english, 1979

20

Nitroxide spin labeled analogs of the non-ionic detergent triton X-100

Richard B. Roman, John F.W. Keana

Journal:

Chemistry and Physics of Lipids

Year:

1982

Language:

english

File:

PDF, 389 KB

english, 1982

21

Synthesis of charged amphipathic nitroxide lipid spin labels and an example of their application in membrane studies

John F.W. Keana, Steven A. Boyd, Debra A. McMillen, Edward M. Bernard, Patricia C. Jost

Journal:

Chemistry and Physics of Lipids

Year:

1982

Language:

english

File:

PDF, 607 KB

english, 1982

22

Synthesis of isosteric and isopolar phosphonate substrate analogues designed as inhibitors for phosphatidylinositol-specific phospholipase C from bacillus cereus

Thottumkara K. Vinod, O. Hayes Griffith, John F.W. Keana

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 280 KB

english, 1994

23

Acetoxylation of 6,7-dialkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones (Qxs) using fuming nitric acid in acetic acid: A facile synthesis of 5-acyloxy-6,7-dialkoxy QXs

Zhang-Lin Zhou, Eckard Weber, John F.W. Keana

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 282 KB

english, 1995

24

Synthesis and properties of chlorophyll-derived nitroxide spin labels

G.Bruce Birrell, Terry D. Lee, O.Hayes Griffith, John F.W. Keana

Journal:

Bioorganic Chemistry

Year:

1978

Language:

english

File:

PDF, 733 KB

english, 1978

25

1-Hydroxy-1,4-dihydroquinoxaline-2,3-diones: Novel antagonists at NMDA receptor glycine sites

Hua Zheng, Stephen A. Espitia, Victor Ilyin, Jon E. Hawkinson, Richard M. Woodward, Eckard Weber, John F.W. Keana

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 141 KB

english, 1996

26

Improved synthesis of myo-inositol 1-(4-nitrophenyl hydrogen phosphate), a chromogenic substrate for phosphatidylinositol-specific phospholipase C

Aleksey V. Rukavishnikov, Tatiana O. Zaikova, O.Hayes Griffith, John F.W. Keana

Journal:

Chemistry and Physics of Lipids

Year:

1997

Language:

english

File:

PDF, 85 KB

english, 1997

27

Intramolecular [2+2] photocycloaddition of juxtaposed 4-pyridone moieties

Barry L. Johnson, Yoshiyasu Kitahara, Timothy J.R. Weakley, John F.W. Keana

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 230 KB

english, 1993

28

1,3-dioxepin

John F.W Keana, Randall H Morse

Journal:

Tetrahedron Letters

Year:

1976

Language:

english

File:

PDF, 128 KB

english, 1976

29

4-azido-2-iodo-3,5,6-trifluorophenylcarbonyl derivatives. A new class of functionalized and iodinated perfluorophenyl azide photolabels

Sui Xiong Cai, John F.W. Keana

Journal:

Tetrahedron Letters

Year:

1989

Language:

english

File:

PDF, 265 KB

english, 1989

30

On the recently reported synthesis of the nitroxide, 2,2,3,3-tetramethylaziridine-1-oxyl

John F.W. Keana, Robert J. Dinerstein, Daniel P. Dolata

Journal:

Tetrahedron Letters

Year:

1972

Language:

english

File:

PDF, 104 KB

english, 1972

31

Racemic progesterone

William S. Johnson, John F.W. Keana, William S. Johnson

Journal:

Tetrahedron Letters

Year:

1963

Language:

english

File:

PDF, 135 KB

english, 1963

32

Photolysis of the stable nitroxide, 3-carbamoyl-2,2,5,5-tetramethylpyrroline-1-oxyl: a new photocycloelimination of nitric oxide

John F.W. Keana, Friedhelm Baitis

Journal:

Tetrahedron Letters

Year:

1968

Language:

english

File:

PDF, 169 KB

english, 1968

33

Synthesis of a new fluorogenic substrate for the assay of phosphoinositide-specific phospholipase C

Aleksey V. rukavishnikov, Miles P. Smith, G. Bruce Birrell, John F.W. Keana, O. Hayes Griffith

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 213 KB

english, 1998

34

A tower-shaped prototypic molecule designed as an atomically sharp tip for AFM applications

Aleksey V. Rukavishnikov, Avinash Phadke, Melissa D. Lee, Donald H. LaMunyon, Pavel A. Petukhov, John F.W. Keana

Journal:

Tetrahedron Letters

Year:

1999

Language:

english

File:

PDF, 227 KB

english, 1999

35

Listeria monocytogenes phosphatidylinositol-specific phospholipase C: activation and allostery

Margret Ryan, Tatiana O. Zaikova, John F.W. Keana, Howard Goldfine, O.Hayes Griffith

Journal:

Biophysical Chemistry

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

36

5567411 Dendritic amplifier molecules having multiple terminal active groups stemming from a benzyl core group

FW Keana John, Vladimir Martin, William Ralston

Journal:

Magnetic Resonance Imaging

Year:

1997

Language:

english

File:

PDF, 103 KB

english, 1997

37

N,N′-disubstituted acetamidines as high affinity sigma receptor ligands

N.Laxma Reddy, James B. Fischer, Kathleen J. Burke-Howie, Peter Barmettler, Michael R. Rhodes, Eckard Weber, John F.W. Keana

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 285 KB

english, 1993

38

A CHROMOGENIC SUBSTRATE FOR THE CONTINUOUS ASSAY OF MAMMALIAN PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C

Aleksey V Rukavishnikov, Margret Ryan, O.Hayes Griffith, John F.W Keana

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 708 KB

english, 1997

39

N-(2-(4-hydroxyphenyl)ethyl)-4-chlorocinnamide: A novel antagonist at the 1a/2B NMDA receptor subtype

Amir P. Tamiz, Edward R. Whittemore, Robert M. Schelkun, Po-Wai Yuen, Richard M. Woodward, Sui-Xiong Cai, Eckard Weber, John F.W. Keana

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 175 KB

english, 1998

40

Synthesis of a new fluorogenic substrate for the continuous assay of mammalian phosphoinositide-specific phospholipase C

Aleksey V. Rukavishnikov, Tatiana O. Zaikova, G.Bruce Birrell, John F.W. Keana, O. Hayes Griffith

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 225 KB

english, 1999

41

Structure-activity relationship for a series of 2-substituted 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indoles: Potent subtype-selective inhibitors of N-methyl-d-aspartate (NMDA) receptors

Amir P. Tamiz, Edward R. Whittemore, Richard M. Woodward, Ravindra B. Upasani, John F.W. Keana

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 315 KB

english, 1999

42

Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists

Zhang-Lin Zhou, Sunil M Kher, Sui Xiong Cai, Edward R Whittemore, Stephen A Espitia, Jon E Hawkinson, Minhtam Tran, Richard M Woodward, Eckard Weber, John F.W Keana

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 316 KB

english, 2003

43

Bis(perfluorophenyl azides) as highly efficient crosslinking agents for poly(vinyl phenol)

Mingdi Yan, M.N Wybourne, John F.W Keana

Journal:

Reactive and Functional Polymers

Year:

2000

Language:

english

File:

PDF, 153 KB

english, 2000

44

Synthesis of phosphonate derivatives of myo-inositol for use in biochemical studies of inositol-binding proteins

M.S. Shashidhar, John F.W. Keana, Johannes J. Volwerk, O. Hayes Griffith

Journal:

Chemistry and Physics of Lipids

Year:

1990

Language:

english

File:

PDF, 674 KB

english, 1990

45

Preparation and application of an affinity matrix for phosphatidylinositol-specific phospholipase C

M.S. Shashidhar, John F.W. Keana, Johannes J. Volwerk, O.Hayes Griffith

Journal:

Chemistry and Physics of Lipids

Year:

1990

Language:

english

File:

PDF, 700 KB

english, 1990

46

A chromogenic substrate for phosphatidylinositol-specific phospholipase C: 4-nitrophenyl myo-inositol-1-phosphate

M.S. Shashidhar, Johannes J. Volwerk, O. Hayes Griffith, John F.W. Keana

Journal:

Chemistry and Physics of Lipids

Year:

1991

Language:

english

File:

PDF, 801 KB

english, 1991

47

Modification of tetrodotoxin with succinic anhydride

Peter N. Strong, John F.W. Keana

Journal:

Bioorganic Chemistry

Year:

1976

Language:

english

File:

PDF, 457 KB

english, 1976

48

6,7,8,9-tetrahydro-3-hydroxy-1H-1-benzazepine-2,5-diones via a diels-alder reaction:antagonists with a non-planar hydrophobic region for NMDA receptor glycine sites

Anthony P. Guzikowski, Jon Hawkinson, Eckard Weber, John F.W. Keana

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 129 KB

english, 1995

49

Nanomedicine and protein misfolding diseases

Alexey V. Kransnoslobodtsev, Luda S. Shlyakhtenko, Egor Ukraintsev, Tatiana O. Zaikova, John F.W. Keana, Yuri L. Lyubchenko

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2005

Language:

english

File:

PDF, 358 KB

english, 2005

50

Monocyclization of N-(2,2-diethoxyethyl)-1,2-diphenylethylamines to the 4-aryl-hydroxy-2,3,4,5-tetrahydro-iH-3-benzazepine ring system

Kyle R. Gee, Eckard Weber, John F.W. Keana

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 166 KB

english, 1993

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